刘丽君,女,博士,教授,自2000年以来主要从事分析化学的科研和教学工作,近年来主要进行分子模拟与药物计算等工作,主持了多项省级科研及教改项目,参加了多项国家自然科学基金的研究。主要研究领域是生物传感器及分子模拟计算,在对电化学生物传感器及药物分子模拟计算的研究中获得了一系列的成果,已发表论文30多篇,其中以第一作者或通讯作者发表SCI收录论文20多篇。
主讲课程:
主要承担《化学分析》、《分析化学实验》、《医用化学》等课程。
主要研究方向:
1.电化学生物传感器
2.分子模拟与药物计算
近5年代表性成果:
1. Rui Liu, Lijun Liu*, Use of Apatinib as a Bait to Fish its Unexpected Kinase Targets from the Hepatocellular Carcinoma Druggable Kinome,J. Comput. Biophys. Chem. 2023, 22 (4): 439-451 2. Deyong He, Rongyuan Yuan, Lijun Liu*, Rational Identification of Conformational and Linear EGFR Epitopes Recognized Specifically by, Respectively, Type-I and Type-II Anti-EGFR Antibodies and Molecular Design of Linear Epitope-Derived Pept,International Journal of Peptide Research and Therapeutics,2023, 29: 45-54
3. Rui Liu, Lijun Liu*,Computational Analysis and Molecular Design of Aromatic Stacking System Between Human ARTD2 Catalytic Domain and its Small-Molecule Inhibitors and Peptidic Ligands,J. Comput. Biophys, Chem. 2022, 21 (5), 529–540
4. Hualong Gu, Lijun Liu*, Molecular modeling and rational design of noncovalent halogen⋯oxygen⋯hydrogen motif at the complex interface of EGFR kinase domain with RALT peptide,Chemical Physics, 2021, 550: 111309
5. Dingwa Zhang, Deyong He, Xiaoliang Pan, Lijun Liu*, Rational design and intramolecular cyclization of hostspot peptide segments at YAP-TEAD4 complex interface,Protein & Peptide Letters, 2020, 27:999-1006