化学发光与生物传感研究方向
  

一、主要研究内容

化学发光新体系的研究;化学发光和其它分离分析技术的联用。主要从事光致发光分析;样品前处理;基于生物分子与层状无机固体的插层组装,实现功能性生物纳米复合材料的制备、表征及分析应用;原子吸收分光光度分析等方面的研究。

二、主要研究人员

龙文清教授(负责人)、刘利民教授(博士)、刘丽君教授(博士),何德勇副教授(博士),黄春芳副教授(在读博士)等。

三、主要研究项目:

1国家自然科学基金项目,基于多元杂化生物纳米层状复合材料的细胞活性氧传感器研究(21265008)(刘利民主持)。

2、江西省自然科学基金项目,基于多元杂化生物纳米层状复合材料的非媒介体生物传感器研究(20114BAB203011)(刘利民主持)。

3、江西省教育厅科学技术研究项目(2002.9-2005.9),高植物蛋白资源的开发研究,(赣教计字[2001]387号,(龙文清主持)。

4、江西省教育厅科学技术研究项目(2010.01-2012.12),亲水有机溶剂双液萃取及与固体基质室温磷光法联用研究,(GJJ10537,(龙文清主持)。

5、江西省自然科学基金项目,环境中酚类污染物的水相分子印迹技术研究(20122BAB213009),(何德勇主持)。

6、江西省教育厅科技计划项目,分子印迹传感器的研究及其在食品安全分析中的应用(GJJ08413),(何德勇主持)。

7、江西省自然科学基金项目,碳纳米管多层膜生物传感器的构筑及其对环境样品中含硫污染物的在线分析研究(2010GZH0073),(刘丽君主持)。

8、江西省教育厅科技计划项目人体血液中还原性巯基化合物的碳纳米管多层膜生物传感器的构建研究(GJJ11526),(刘丽君主持)。

四、主要研究成果:

1Limin Liu et al., A novel mediator-free biosensor based on co-intercalation of DNA and hemoglobin in the interlayer galleries of α-zirconium phosphate, Biosensors and Bioelectronics, 2010, 25, 12, 2627–2632.

2Limin Liu et al., pH-induced fabrication of DNA/chitosan/α-ZrP nanocomposite and DNA release, Nanotechnology, 2010, 21, 10, 105102.

3Wen-Qing Long et al., Studies on properties and application of non-protected room temperature phosphorescence of propranolol, Spectrochimica Acta Part A 2002, 58 (10): 2185-2191.

4龙文清. 色氨酸无保护流体室温燐光和胶束增稳室温燐光性质的比较, 分析化学, 2005, 33 (2): 217-220.

5龙文清. 吲哚-3-丁酸无保护流体室温燐光和胶束增稳室温燐光性质的比较, 光谱学与光谱分析, 2005, 25 (4): 624-627.

6龙文清. 浊点萃取-胶束增稳室温燐光法测定水样中痕量α-萘乙酸, 分析化学, 2005, 33 (7): 1013-1015.

7龙文清. 丙酮和乙醇双水相萃取、荧光法测定痕量维生素B2, 光谱学与光谱分析, 2007, 27 (10): 2098-2101.

8龙文清. 有机溶剂对2-萘磺酸钠无保护流体室温燐光的影响, 分析化学, 2004, 32 (5): 693.

9、黄春芳, . 配合物[Mn(NPA)2(Phen)(H2O)2]的合成、晶体结构及热稳定性, 无机化学学报, 2007, 23 (12): 2035-2038.

10 Deyong He, Zhujun Zhang, Ying Huang, Chemiluminescence microflow injection analysis system on a chip for the determination of sulfite in food. Analytical Letters, 2005, 38(4): 563-573.

11Deyong He, Zhujun Zhang, Ying Huang, Chemiluminescence microflow injection analysis system on a chip for the determination of uric acid without enzyme. Luminescence, 2005, 20:271-275.

12 Deyong He, Zhujun Zhang, Chao He, Investigation on the interaction between dihydroxybenzene and Fe3+-H2O2-Rh6G system based on the enhancing chemiluminescence. Luminescence, 2006, 21(1): 15-19.

13 Deyong He, Zhujun Zhang, Houjiang Zhou, Ying Huang, Micro flow sensor on a chip for the determination of terbutaline in human serum based on Chemiluminescence and a molecularly imprinted polymer. Talanta 2006(69): 1215-1220.

14Deyong He, Zhujun Zhang, Ying Huang, Yufei Hu, Chemiluminescence microflow injection analysis system on a chip for the determination of nitrite in food. Food Chemistry2007101667-672.

15 Deyong He, Shuhua He, Zhujun Zhang A chemiluminescence reaction between hydroxyl radical and rhodamine 6G and its applications. Analytical letters. 2007, 40(15), 2935-2945.

16Lijun Liu, Xin Jin, Shaoming Yang, Zhichun Chen, Xianfu Lin, A highly sensitive biosensor with (Con A/HRP)n multilayer films based on layer-by-layer technique for the detection of reduced thiols. Biosensors and Bioelectronics 2007, 22, 3210-3216.

17 Lijun Liu, Zhichun Chen, Shaoming Yang, Xin Jin and Xian-Fu Lin A novel inhibition biosensor constructed by layer-by-layer technique based on biospecific affinity for the determination of sulfide, Sensors and Actuators B: Chemical, 2008, 129, 218-224.

18Lijun Liu, Fu Zhang, Fengna Xi, Xianfu Lin, Highly sensitive biosensor based on bionanomultilayer with water-soluble multiwall carbon nanotubes for determination of phenolics. Biosensors and Bioelectronics 2008, 24, 306-312.

19 Lijun Liu, Fu Zhang, Fengna Xi, Xianfu Lin, Uniform bionanomultilayer constructed with soluble multiwall carbon nanotubes and its application as biosensor. Journal of Electroanalytical Chemistry 2008, 623, 135-141.